Author: isdp

In 2023, the U.S. Surgeon General declared social connection as a public health priority, emphasizing the critical role that social connection plays in transforming health and well-being across individuals and communities. In line with this call to action, it is essential to understand the normative neurobiological development of social relationships, including how relationships may buffer against the negative effects of stress and promote adaptive outcomes. In this symposium, we will present on various physiological and neural mechanisms by which different types of social partners affect developmental outcomes. The first two presentations focus on who can effectively buffer the hypothalamic-pituitary-adrenal (HPA) response to stress in children and adolescents. The first presentation explores whether “sharing the load” of a stressor with a close friend influences cortisol reactivity to the stressor in adolescence. The second presentation examines whether siblings can buffer the cortisol stress response for children and adolescents. The third presentation features a non-human animal model of social bonding, highlighting the neural circuitry that underlies pair bonding behaviors with romantic partners in the socially monogamous prairie vole across different age groups. The fourth presentation describes associations between caregiver-child relationships and the development of the corticolimbic tract (structure, function, and connectivity) in humans, and how these neurobiological differences relate to well-being and resilient functioning. Finally, Dr. Megan Gunnar, an expert on the neurobiological development of social relationships, will serve as the discussant, highlighting integrative themes across all four presentations and facilitating discussion of implications and future directions. In line with ISDP’s priorities, this symposium will feature research across multiple species, biological systems, methodologies, and developmental stages.

The gut microbiome has been trans-diagnostically linked with psychopathology in adults, and a wave of recent research has suggested that differences in the diversity and composition of the gut microbiome in early life may be associated with differential risk for the development of psychopathology. The gut microbiome undergoes a critical period of development in early life, overlapping with sensitive periods in other key physiological and stress response systems, making questions about connections between the gut microbiome and psychopathology particularly important to consider from a developmental perspective. In this symposium, we explore the role of the gut microbiome in developmental psychopathology, the state of the literature in this growing line of inquiry, and identify areas for future research. In the first presentation, Dr. Sarah Vogel will present longitudinal associations between development of the gut microbiome throughout infancy and behavioral measures of fearfulness and negative affectivity in early childhood. Next, Dr. Patricia Brennan will integrate perspectives from the social determinants of health and developmental origins of health and disease (DOHaD) frameworks to discuss connections between prenatal stress, the infant gut microbiome, and child behavior problems in two samples of African American infants and their mothers. Naomi Gancz will then discuss connections between the gut microbiome and internalizing symptoms across childhood and the role of childhood adversity in moderating gut-behavior associations. Finally, Dr. Harikesh Dubey will present some experimental work examining the effects of fecal transplant procedures in mice and implications for anxiolytic behavior, with an emphasis on neural mechanisms, including myelination and dendritic complexity. This symposium will integrate research perspectives from across disciplines, species, domains, and developmental timing to contextualize the state of our scientific understanding of the role of the gut microbiome in developmental psychopathology and inspire discussion about the potential future directions for research and intervention.

Parents’ processing of infant cues (e.g., infant emotional expressions, vocalizations) is expected to shape their caregiving behaviors. Event-related potentials (ERPs), derived from electroencephalography (EEG), are particularly valuable to investigating neural processing of salient infant cues in expectant and postpartum women with their high temporal sensitivity in measuring the magnitude and efficiency of infant cue processing, resonating with the intuitive nature of parenting. Given the cost effectiveness and ease of implementation, EEG/ERP is also advantageous for large-scale studies of parenting to ensure more reliable and replicable results. Although EEG/ERP research has demonstrated that infant emotional faces are prioritized across early and late stages of processing, questions remain regarding the maternal factors that shape variation in women’s neural responding to infant emotional faces, and in turn, child development. The proposed symposium comprises four presentations that capture new directions in maternal EEG/ERP research designed to address these gaps and identify targets for parenting interventions. In this symposium, a brief primer on EEG/ERP will be provided as part of the introduction to the speakers and overview of the symposium. The first two presentations clarify the role of psychological risk factors on (expectant) mothers’ ERPs to infant emotional expressions. In the first presentation, Kristin Bernard, PhD, will discuss the importance of mothers’ own early attachment experiences in shaping neural processing of infant cues in 81 mothers, highlighting the importance of incorporating multiple assessments of early attachment experiences in contextualizing findings. Building on this work, in the second presentation, Tingyan Liu, BS, will showcase the value of moving beyond one variable of psychological risk to considering the unique contributions of depression and attachment insecurity to maternal neural processing of infant cues in a sample of 200 pregnant women. In recognizing that an important goal of maternal brain research more broadly is to inform understanding of child development, the second two presentations demonstrate the downstream significance of mothers’ neural processing of emotional expressions for children’s development. In the third presentation, Sarah Peoples, MSc, employs a novel approach to considering neural synchrony in face processing between 139 mothers and their infants, and demonstrates that how synchrony is related to infant internalizing symptoms depends on mothers’ symptomatology. Finally, in the fourth presentation, Kathryn Wall, MPhil, will present data for the first time linking maternal neural responses to infant cues with infant developmental outcomes in 94 mother-infant dyads. Taken together, these studies showcase innovation in the application of EEG/ERP to study psychological processes contributing to maternal neural processing of infant cues and the significance for child development.

ISDP and the DEI Committee are seeking investigators from historically marginalized and underrepresented communities to apply for our inaugural DEI Committee-sponsored symposium, with intention to present at the 2024 Annual Meeting (Chicago, IL, Oct. 2nd-4th). Early-career investigators ((from graduate students to within seven years of earning a Ph.D., M.D., Psy.D., etc.) investigators are especially encouraged to apply.